Our Novel Approach to Perfecting Topical Cannabinoids

Typical CBD (or CBG) creams are not very effective. Our mission is simple: make a cannabinoid cream that actually works. Cannabinoids have shown promise in many applications by interacting with the human endocannabinoid system¹. To take advantage of these fascinating molecules, we developed a high potency cream that is optimized for penetration on all areas of skin and suitable for all skin types. This was done by carefully optimizing three key factors:

  1. Penetration
  2. Sourcing
  3. Formulation

Penetration

Topical Cannabinoids Have Typically Been Ineffective Due to Issues Penetrating the Skin²

The success of 2.AG starts with designing the delivery vehicle. Our patent pending intercellular carrier is formulated to bring the cannabinoids to muscles and joints through the intercellular route, or between the cells. It requires balancing many competing factors to allow the cream to move through the hydrated and lipid-heavy layers of your skin.

Most CBD topicals are mixed in premade bases of oils, butters, waxes, and salves. These do not penetrate well past the upper layers of your skin.

The design of a carrier to move cannabinoids through the skin is complex.

The amount and type of penetration enhancers, exfoliators, moisturizers, cannabinoids, and solvents all effect penetration, feel, and overall effectiveness. Each one of these is perfectly optimized to create a cannabinoid cream that actually works.

Sourcing

Selecting the Highest-Purity Cannabinoid Isolates Available

Cannabinoids have demonstrated significant therapeutic potential³. Our cannabinoids are the most potent and pure isolates available. We constantly evaluate, test, and reassess our cannabinoid isolates to ensure our products utilize the best possible bulk product to combine with our delivery vehicle.

CBG Isolate
CBD Isolate

Carefully Formulated for Long Term Use, Even on Sensitive Skin

Formulation

With all of these factors perfected, our topical cannabinoid complex can deliver unmatched results

Rapid Relief Cream

12 reviews

10,000 mg CBG 5% | CBD 5%

Up to 200 Applications

Our proprietary rapid relief cream with deep penetrating, fast acting topical CBG and CBD isolates. We combine the highest concentration of CBG and CBD available with our perfectly optimized delivery vehicle to deliver targeted relief into muscles, joints, and nerves. All of our products are completely THC free. Most users feel results within 3 minutes*.

  • 2 cannabinoids with different effects
  • 5 key ingredients used in delivery vehicle
  • 3 minutes to results*

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Unlocking the Potential of Topical Cannabinoids

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1. Lu HC, Mackie K. Review of the Endocannabinoid System. Biol Psychiatry Cogn Neurosci Neuroimaging. 2021 Jun;6(6):607-615. doi: 10.1016/j.bpsc.2020.07.016. Epub 2020 Aug 1. PMID: 32980261; PMCID: PMC7855189.

2. Kirk RD, Akanji T, Li H, Shen J, Allababidi S, Seeram NP, Bertin MJ, Ma H. Evaluations of Skin Permeability of Cannabidiol and Its Topical Formulations by Skin Membrane-Based Parallel Artificial Membrane Permeability Assay and Franz Cell Diffusion Assay. Med Cannabis Cannabinoids. 2022 Oct 10;5(1):129-137. doi: 10.1159/000526769. PMID: 36467778; PMCID: PMC9710319.

3. Henshaw FR, Dewsbury LS, Lim CK, Steiner GZ. The Effects of Cannabinoids on Pro- and Anti-Inflammatory Cytokines: A Systematic Review ofIn VivoStudies. Cannabis Cannabinoid Res. 2021 Jun;6(3):177-195. doi: 10.1089/can.2020.0105. Epub 2021 Apr 28. PMID: 33998900; PMCID: PMC8266561.